In silico and in vitro biophysical screening methods for proteins

PhD defence, Monday, 14 January 2019. Adriana-Michelle Wolf Pérez.

2019.01.14 | Rikke J. Ljungmann

Adriana-Michelle Wolf Pérez

Adriana-Michelle Wolf Pérez’s research focuses on the development and validation of innovative technologies for the rational design of protein therapeutics. In collaboration with the University of Cambridge, ETH Zurich, Aarhus University and Novo Nordisk, she developed and applied several methods to generate novel opportunities to streamline and guide the development of therapeutic antibodies.

The outcomes of her studies demonstrate that computational methods are powerful time- and cost-effective tools to facilitate and accelerate the selection of developable protein therapeutics.      

The PhD degree was completed at the Interdisciplinary Nanoscience Center (iNANO), Science and Technology, Aarhus University.

This résumé was prepared by the PhD student.

Time: Monday, 14 January 2019 at 13.15
Place: Building 1593, room 012, the Lecture Theatre, iNANO House, Gustav Wieds Vej 14, Aarhus University, 800 Aarhus C.
Title of PhD thesis: In silico and in vitro biophysical screening methods for proteins
Contact information: Adriana-Michelle Wolf Pérez, e-mail: adriana.wolf@inano.au.dk
Members of the assessment committee:
Principal Scientist, Ph.D., MRSC Bojana Popovic, MedImmune, Antibody Discovery and Protein Engineering, Cambridge, Great Britain
Professor, PhD Peter Westh, Department of Biotechnology and Biomedicine, Technical University of Denmark
Professor Jan Skov Pedersen (chair), iNANO and Department of Chemistry, Aarhus University
Main supervisor:
Professor Daniel Otzen, iNANO and Department of Molecular Biology and Genetics, Aarhus University
Co-supervisors:
Professor Michele Vendruscolo, Cambridge University
Dr. Nikolai Lorenzen, Novo Nordisk A/S
Dr. Søren Berg Padkjær, Novo Nordisk A/S
Language: The PhD thesis will be defended in English

The defence is public.
The dissertation is available for reading at the Graduate School of Science and Technology/GSST, Ny Munkegade 120, building 1520 and 1521, 8000 Aarhus C.

PhD defence
12183 / i43