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POSTPONED: Flipping the switch on protein production

PhD defence, Friday 3 April 2020, Thuy Jane Dinh Nguyen.

2020.04.03 | Mie Meulengracht Christensen

Thuy Jane Dinh Nguyen

Proteins are the workhorses of the cell and they are crucial for the structure, function and regulation of cells. Being able to regulate the production of proteins in an efficient manner would have an impact on not only fundamental research but also on the food industry and pharmaceutical industry. During her studies, Thuy Jane Dinh Nguyen has developed a nucleic acid based protein regulator. The regulator exploits the advantageous properties of an artificial nucleic acid and it is able to bind DNA and RNA in a very stable manner. It is demonstrated that the processes of protein production, which are based on DNA and RNA, can be stopped using the regulator. The new research findings contribute to the highly relevant topics of protein regulation and antisense technology.

The PhD degree was completed at the Interdisciplinary Nanoscience Center (iNANO), Faculty of Natural Sciences, Aarhus University.

This résumé was prepared by the PhD student.

Friday 3 April 2020 at 13.15
Place: Building 1514, room 213, Auditorium 1, Department of Chemistry, Aarhus University
Title of PhD thesis: Exploring the Potential of Modified Oligonucleotides
Contact information: Thuy Jane Dinh Nguyen, e-mail: tjn.jane@gmail.com, tel.: +4561697491
Members of the assessment committee:
Professor Poul Nielsen, Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Denmark
Professor Dr. Andriy Mokhir, Department of Chemistry and Pharmacy, Friedrich Alexander University Erlangen-Nürnberg, Germany
Professor Troels Skrydstrup (chair), iNANO and Department of Chemistry, Aarhus University
Main supervisor:
Professor Kurt V. Gothelf, iNANO and Department of Chemistry, Aarhus University
Language: The PhD dissertation will be defended in English

The defence is public.
The PhD thesis is available for reading at the Graduate School of Science and Technology/GSST, Ny Munkegade 120, building 1521, 8000 Aarhus C.

PhD defence
12183 / i43